News Updates:
June 10, 2005,
Eli Lilly pays $700m to settle Zyprexa claims
April 11, 2005, Reuters,
FDA Orders Black Box Warning For Zyprexa Label
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Zyprexa is an
“atypical antipsychotic medication” which acts as a mood
stabilizer. It has been frequently used to treat
schizophrenia by controlling hallucinations, delusions,
apathy and withdrawal. Zyprexa is also FDA approved for
the treatment of Bi-Polar Mania. Zyprexa was once described as
being "safer and more effective" in the treatment of
schizophrenia than any other previous drug.
In 1996, Zyprexa was
approved for sale in the United States. For many years,
remarkable recoveries seemed to confirm early excitement
about this medication. The first generation of
antipsychotic drugs had terrible side effects, such as
dry mouth, stiffness, and trembling, and patients
stopped using them as a result. Zyprexa seemed to have
fewer side effects than previous antipsychotic drugs.
Zyprexa appeared so
successful initially, that doctors began prescribing it
for manic depression, Alzheimer's disease, personality
disorders, non-psychotic depression and for severe
aggression in children. Sales of the drug soared.
Doctors wrote close to 15 million prescriptions for
Zyprexa in 2002 alone, making it the one of the
highest-selling drugs, behind cholesterol-lowering
drugs, ulcer drugs, and antidepressants.
Zyprexa is available as
tablets that can be taken once a day in varying
strengths. It had earlier been prescribed as being
easily tolerated for most patients and that routine
blood monitoring was unnecessary. Unfortunately, this
later was proved to be incorrect.
Zyprexa and other
atypical drugs are no longer viewed as “wonder drugs.”
Their success is now described as “modest at best.”
Researchers increasingly suspect that atypical drugs,
such as Zyprexa, may cause serious side effects. Most
serious is the development of diabetes that in some
cases may lead to death. There has also been a close
association between Zyprexa and pancreatitis.
In September 2003, as a
result of hundreds of adverse reactions and reported
complaints (including hyperglycemia, diabetes,
ketoacidosis, pancreatitis, and other related
conditions), the FDA ordered that the warning labels be
changed on the Zyprexa bottles to alert patients of the
severe complications associated with this product.
(Japan published safety warnings two years before the
U.S.)
Reported side effects
associated with Zyprexa have included:
- Weight gains in
excess of 65 pounds
- Diabetes,
hyperglycemia, or other glucose abnormalities (some
patients have even died from developing diabetes after
taking Zyprexa)
- Heart attacks and
comas
- Neuroleptic
malignant syndrome
- Pancreatitis
Consumer groups believe
that the FDA had done too little too late to warn
doctors and patients about the risks associated with
Zyprexa. The failure to give adequate, and earlier
warnings, is one of the main allegations involved in
Zyprexa lawsuits.
Eli Lilly, the
manufacturer of Zyprexa, has argued that Zyprexa's
safety is supported by two of their self-sponsored
studies. These two studies demonstrated that Zyprexa had
no diabetes-inducing effects. According to doctors at
the diabetes care center at the University of North
Carolina, too few patients were studied to detect a less
common Zyprexa side effect.
If you, or a loved one
has been taking Zyprexa and subsequently developed
diabetes, Pancreatitis, hyperglycemia, or you have a
family member who has died from a diabetes-induced heart
attack, you should consult with an attorney to determine
if you may be eligible for compensation.
Commonly Asked
Questions Related to Zyprexa
I am currently taking this medication; are there
precautions that I should be taking?
- Call your doctor if
you feel that you have developed any unusual symptoms
since being on the medication.
- Also call your
doctor immediately if you have uncontrollable
movements of your mouth, tongue, cheeks, jaw, arms, or
legs.
- Zyprexa may cause
dizziness or drowsiness. Use caution when driving,
operating machinery, or performing other hazardous
activities.
- Use alcohol
cautiously. Alcohol may increase drowsiness and
dizziness while you are taking Zyprexa.
- Avoid becoming
overheated. It is easy to become dangerously
dehydrated while you are taking Zyprexa. Use caution
in hot weather and during exercise; drink plenty of
water.
Do other medications
affect Zyprexa?
In some instances, yes,
so it is very important to tell your doctor and your
pharmacist about all the medicines (including over-the
counter) and vitamins, that you are taking before
beginning Zyprexa.
Zyprexa may increase
the effects of medicines that are used to control high
blood pressure. This could lead to very low blood
pressure, dizziness, and fainting. Zyprexa may also
increase the effects of drugs that cause drowsiness,
including antidepressants, alcohol, antihistamines,
sedatives, pain relievers, anxiety medicines, muscle
relaxants, and any other drug that makes you feel sleepy
or relaxed. Zyprexa may decrease the effects of drugs
used to treat Parkinson's disease which could lead to
worsening Parkinson’s symptoms.
Why were patients in
Japan warned earlier about this drug’s adverse
reactions, than US patients?
Drug companies in the
United States spend millions of dollars on drug
lobbyists and money talks in our economy, but other
countries generally have less bureaucratic red tape,
which may be the reason that Japan citizens were warned
earlier than those in the US.
How much does it
cost to hire an attorney for a Zyprexa lawsuit?
In most cases, it costs
you nothing. Most attorneys are hired on a contingency
basis meaning they are paid a portion of your
settlement. If you do not win your case, the attorney
will not get paid. You have nothing to lose by
contacting an attorney immediately.
Zyprexa Lawyers / Attorneys
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Arthur M. Blue Law Office, P.A.,
Personal Injury lawyers, Carthage & Southern Pines, North Carolina -
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Brinkley Walser, PLLC,
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Crouse Law Offices, James
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including
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Rosen & Rosen,
Medical
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Abuse, Hollywood, FL - (954) 981-1852
Raleigh Personal Injury Lawyers
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1(800)434-8399
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Washington
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